Macf1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comMacf1 ELISA Kit for Rat(Rattus norvegicus)

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Macf1 (Gene name),

Microtubule-actin cross-linking factor 1 (Protein name ), MACF1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Macf1(Acf7;Aclp7;Macf);

Protein name:

Microtubule-actin cross-linking factor 1;

Alternative:

Actin cross-linking family 7;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with MAPRE1, CLASP1, CLASP2 and GOLGA4 (By similarity). Interacts with AXIN1 and LRP6. Found in a complex composed of MACF1, APC; AXIN1, CTNNB1 and GSK3B.

Function:

F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells.

Subcellular Location:

Cytoplasm cytoskeleton Cytoplasm Membrane Cell membrane Cell projection ruffle membrane Localizes to the tips of microtubules. APC controls its localization to the cell membrane which is critical for its function in microtubule stabilization. The phosphorylated form is found in the cytoplasm while the non-phosphorylated form associates with the microtubules.

Protein Attributes:

Sequence length:

5430

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SRRGLTKPSK | IPTMSKKTTT | ASPRTPCPKR |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00307

UniGene:

Rn.221899

UniGene:

Rn.213155

Uniprot:

D3ZHV2

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ELISA Kit for Rat Microtubule-actin cross-linking factor 1

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E15471r

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ELISA Kit for Rat Microtubule-actin cross-linking factor 1

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E15471h

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96T

ELISA Kit for Rat Microtubule-actin cross-linking factor 1

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E15471m

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ELISA Kit for Rat Microtubule-actin cross-linking factor 1

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E15471h

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96T

CLIA Kit for Rat Microtubule-actin cross-linking factor 1

Cat.:

U15471h

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96T

CLIA Kit for Rat Microtubule-actin cross-linking factor 1

Cat.:

U15471m

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96T

CLIA Kit for Rat Microtubule-actin cross-linking factor 1

Cat.:

U15471h

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MSDS:

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Packing:

96T

CLIA Kit for Rat Microtubule-actin cross-linking factor 1

Cat.:

U15471r

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96T

Polyclonal Antibody for Rat Microtubule-actin cross-linking factor 1

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P15471Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat Microtubule-actin cross-linking factor 1

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P15471Rb-m

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40ug/0.2ml

Polyclonal Antibody for Rat Microtubule-actin cross-linking factor 1

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P15471Rb-r

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40ug/0.2ml

Polyclonal Antibody for Rat Microtubule-actin cross-linking factor 1

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P15471Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Microtubule-actin cross-linking factor 1

Protein for Rat Microtubule-actin cross-linking factor 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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